Cargando…

Estrogen Enhances Dendrite Spine Function and Recovers Deficits in Neuroplasticity in the prpTDP-43(A315T) Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) attacks the corticomotor system, with motor cortex function affected early in disease. Younger females have a lower relative risk of succumbing to ALS than males and older females, implicating a role for female sex hormones in disease progression. However, the mec...

Descripción completa

Detalles Bibliográficos
Autores principales: Handley, Emily E., Reale, Laura A., Chuckowree, Jyoti A., Dyer, Marcus S., Barnett, Grace L., Clark, Courtney M., Bennett, William, Dickson, Tracey C., Blizzard, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016039/
https://www.ncbi.nlm.nih.gov/pubmed/35249200
http://dx.doi.org/10.1007/s12035-022-02742-5