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Estrogen Enhances Dendrite Spine Function and Recovers Deficits in Neuroplasticity in the prpTDP-43(A315T) Mouse Model of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) attacks the corticomotor system, with motor cortex function affected early in disease. Younger females have a lower relative risk of succumbing to ALS than males and older females, implicating a role for female sex hormones in disease progression. However, the mec...
Autores principales: | Handley, Emily E., Reale, Laura A., Chuckowree, Jyoti A., Dyer, Marcus S., Barnett, Grace L., Clark, Courtney M., Bennett, William, Dickson, Tracey C., Blizzard, Catherine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016039/ https://www.ncbi.nlm.nih.gov/pubmed/35249200 http://dx.doi.org/10.1007/s12035-022-02742-5 |
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