A Mutant Variant of E2F4 Triggers Multifactorial Therapeutic Effects in 5xFAD Mice

Alzheimer’s disease (AD) has a complex etiology, which requires a multifactorial approach for an efficient treatment. We have focused on E2 factor 4 (E2F4), a transcription factor that regulates cell quiescence and tissue homeostasis, controls gene networks affected in AD, and is upregulated in the...

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Detalles Bibliográficos
Autores principales: López-Sánchez, Noelia, Ramón-Landreau, Morgan, Trujillo, Cristina, Garrido-García, Alberto, Frade, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016056/
https://www.ncbi.nlm.nih.gov/pubmed/35254651
http://dx.doi.org/10.1007/s12035-022-02764-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016056/
https://www.ncbi.nlm.nih.gov/pubmed/35254651
http://dx.doi.org/10.1007/s12035-022-02764-z

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