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METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition

Papillary thyroid cancer (PTC) is a common endocrine system malignancy all over the world. Aberrant expression of six transmembrane epithelial antigen of the prostate 2 (STEAP2) has been functionally associated with cancer progression in many cancers. Nevertheless, its biological function in PTC is...

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Detalles Bibliográficos
Autores principales: Zhu, Yue, Peng, Xinzhi, Zhou, Qianlei, Tan, Langping, Zhang, Cheng, Lin, Shaojian, Long, Miaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016063/
https://www.ncbi.nlm.nih.gov/pubmed/35436987
http://dx.doi.org/10.1038/s41419-022-04817-6