Cargando…

METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition

Papillary thyroid cancer (PTC) is a common endocrine system malignancy all over the world. Aberrant expression of six transmembrane epithelial antigen of the prostate 2 (STEAP2) has been functionally associated with cancer progression in many cancers. Nevertheless, its biological function in PTC is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Yue, Peng, Xinzhi, Zhou, Qianlei, Tan, Langping, Zhang, Cheng, Lin, Shaojian, Long, Miaoyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016063/ https://www.ncbi.nlm.nih.gov/pubmed/35436987 http://dx.doi.org/10.1038/s41419-022-04817-6

Ejemplares similares

Linc01278 inhibits the development of papillary thyroid carcinoma by regulating miR-376c-3p/DNM3 axis
por: Lin, Shaojian, et al.
Publicado: (2019)

Long non‐coding RNA TNRC6C‐AS1 promotes methylation of STK4 to inhibit thyroid carcinoma cell apoptosis and autophagy via Hippo signalling pathway
por: Peng, Xinzhi, et al.
Publicado: (2019)

Alternative splicing of METTL3 explains apparently METTL3-independent m(6)A modifications in mRNA
por: Poh, Hui Xian, et al.
Publicado: (2022)

Circular RNA_0057209 Acts as ceRNA to Inhibit Thyroid Cancer Progression by Promoting the STK4-Mediated Hippo Pathway via Sponging MicroRNA-183
por: Peng, Xinzhi, et al.
Publicado: (2022)

METTL3-mediated m(6)A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial–mesenchymal transition
por: Wang, Yuwei, et al.
Publicado: (2023)

METTL3-mediated m(6)A mRNA modification of FBXW7 suppresses lung adenocarcinoma
por: Wu, Yingtong, et al.
Publicado: (2021)

METTL3 Is Involved in the Development of Graves’ Disease by Inducing SOCS mRNA m6A Modification
por: Song, Rong-hua, et al.
Publicado: (2021)

Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m(6)A-mediated degradation of STEAP3 mRNA
por: Zhou, Li, et al.
Publicado: (2022)

DARS-AS1 recruits METTL3/METTL14 to bind and enhance DARS mRNA m(6)A modification and translation for cytoprotective autophagy in cervical cancer
por: Zhu, Miaohua, et al.
Publicado: (2022)

METTL3 Contributes to Osteosarcoma Progression by Increasing DANCR mRNA Stability via m6A Modification
por: Zhou, Xinying, et al.
Publicado: (2022)

HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification
por: Yang, Zhi, et al.
Publicado: (2020)

METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy
por: Jiang, Ling, et al.
Publicado: (2022)

Lactylation of METTL16 promotes cuproptosis via m(6)A-modification on FDX1 mRNA in gastric cancer
por: Sun, Lianhui, et al.
Publicado: (2023)

Corrigendum: METTL3 contributes to osteosarcoma progression by increasing DANCR mRNA stability via m6A modification
por: Zhou, Xinying, et al.
Publicado: (2023)

METTL3-mediated m(6)A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung
por: Cheng, Cheng, et al.
Publicado: (2020)

MiR-4729 regulates TIE1 mRNA m6A modification and angiogenesis in hemorrhoids by targeting METTL14
por: Liu, Te, et al.
Publicado: (2021)

PLAA suppresses ovarian cancer metastasis via METTL3-mediated m(6)A modification of TRPC3 mRNA
por: Shen, Zhangjin, et al.
Publicado: (2022)

METTL14 promotes migration and invasion of choroidal melanoma by targeting RUNX2 mRNA via m6A modification
por: Zhang, Xi, et al.
Publicado: (2022)

METTL3-mediated m6A modification of SIRT1 mRNA inhibits progression of endometriosis by cellular senescence enhancing
por: Wang, Xiaotong, et al.
Publicado: (2023)

METTL3-mediated N(6)-methyladenosine mRNA modification enhances long-term memory consolidation
por: Zhang, Zeyu, et al.
Publicado: (2018)

METTL3-mediated m(6)A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway
por: Han, Hui, et al.
Publicado: (2021)

METTL3-mediated m6A modification of Bcl-2 mRNA promotes non-small cell lung cancer progression
por: Zhang, Yongxi, et al.
Publicado: (2021)

Expression and prognostic analyses of the significance of STEAP1 and STEAP2 in lung cancer
por: Liu, Tianshu, et al.
Publicado: (2022)

The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells
por: Leoni, Cristina, et al.
Publicado: (2023)

Differences in miRNA and mRNA Profile of Papillary Thyroid Cancer Variants
por: Stokowy, Tomasz, et al.
Publicado: (2016)

Integrated Characterization of MicroRNA and mRNA Transcriptome in Papillary Thyroid Carcinoma
por: Mohamad Yusof, Azliana, et al.
Publicado: (2018)

Expression of STEAP1 and STEAP1B in prostate cell lines, and the putative regulation of STEAP1 by post-transcriptional and post-translational mechanisms
por: Gomes, Inês M., et al.
Publicado: (2014)

The methyltransferase METTL3 promotes tumorigenesis via mediating HHLA2 mRNA m6A modification in human renal cell carcinoma
por: Zhu, Dawei, et al.
Publicado: (2022)

Mettl3-mediated mRNA m(6)A modification controls postnatal liver development by modulating the transcription factor Hnf4a
por: Xu, Yan, et al.
Publicado: (2022)

Retraction Notice to: METTL3-mediated m(6)A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung
por: Cheng, Cheng, et al.
Publicado: (2023)

[Corrigendum] METTL3‑mediated m6A modification of Bcl‑2 mRNA promotes non‑small cell lung cancer progression
por: Zhang, Yongxi, et al.
Publicado: (2023)

RNA m(6)A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway
por: Cai, Jiarong, et al.
Publicado: (2019)

Mettl3-mediated mRNA m(6)A methylation promotes dendritic cell activation
por: Wang, Huamin, et al.
Publicado: (2019)

METTL3-mediated m(6)A modification is required for cerebellar development
por: Wang, Chen-Xin, et al.
Publicado: (2018)

METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer
por: Chen, Xiaoxiang, et al.
Publicado: (2020)

METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progression of stomach adenocarcinoma
por: Zhang, Zhijin, et al.
Publicado: (2023)

METTL3 and ALKBH5 oppositely regulate m(6)A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes
por: Song, Huiwen, et al.
Publicado: (2019)

The m6A Methyltransferase METTL14-Mediated N6-Methyladenosine Modification of PTEN mRNA Inhibits Tumor Growth and Metastasis in Stomach Adenocarcinoma
por: Yao, Qi, et al.
Publicado: (2021)

Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m(6)A Modification of MAT2A Pre-mRNA by METTL16
por: Chen, Peng-Bo, et al.
Publicado: (2022)

The m6A Methyltransferase METTL3-Mediated N6-Methyladenosine Modification of DEK mRNA to Promote Gastric Cancer Cell Growth and Metastasis
por: Zhang, Hui-Min, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n2f1t2q00r189p4fgdpe1t7fu8