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Cell-in-cell structure mediates in-cell killing suppressed by CD44

Penetration of immune cells into tumor cells was believed to be immune-suppressive via cell-in-cell (CIC) mediated death of the internalized immune cells. We unexpectedly found that CIC formation largely led to the death of the host tumor cells, but not the internalized immune cells, manifesting typ...

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Detalles Bibliográficos
Autores principales: Su, Yan, Huang, Hongyan, Luo, Tianzhi, Zheng, You, Fan, Jie, Ren, He, Tang, Meng, Niu, Zubiao, Wang, Chenxi, Wang, Yuqi, Zhang, Zhengrong, Liang, Jianqing, Ruan, Banzhan, Gao, Lihua, Chen, Zhaolie, Melino, Gerry, Wang, Xiaoning, Sun, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016064/
https://www.ncbi.nlm.nih.gov/pubmed/35436988
http://dx.doi.org/10.1038/s41421-022-00387-1