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Identification of potent inhibitors of NEK7 protein using a comprehensive computational approach

NIMA related Kinases (NEK7) plays an important role in spindle assembly and mitotic division of the cell. Over expression of NEK7 leads to the progression of different cancers and associated malignancies. It is becoming the next wave of targets for the development of selective and potent anti-cancer...

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Detalles Bibliográficos
Autores principales: Aziz, Mubashir, Ejaz, Syeda Abida, Tamam, Nissren, Siddique, Farhan, Riaz, Naheed, Qais, Faizan Abul, Chtita, Samir, Iqbal, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016071/
https://www.ncbi.nlm.nih.gov/pubmed/35436996
http://dx.doi.org/10.1038/s41598-022-10253-5