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Cooperative effects of RIG-I-like receptor signaling and IRF1 on DNA damage-induced cell death

Properly responding to DNA damage is vital for eukaryotic cells, including the induction of DNA repair, growth arrest and, as a last resort to prevent neoplastic transformation, cell death. Besides being crucial for ensuring homeostasis, the same pathways and mechanisms are at the basis of chemoradi...

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Detalles Bibliográficos
Autores principales: Zander, David Y., Burkart, Sandy S., Wüst, Sandra, Magalhães, Vladimir G., Binder, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016077/
https://www.ncbi.nlm.nih.gov/pubmed/35436994
http://dx.doi.org/10.1038/s41419-022-04797-7