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Allele-specific analysis reveals exon- and cell-type-specific regulatory effects of Alzheimer’s disease-associated genetic variants

Elucidating regulatory effects of Alzheimer’s disease (AD)-associated genetic variants is critical for unraveling their causal pathways and understanding the pathology. However, their cell-type-specific regulatory mechanisms in the brain remain largely unclear. Here, we conducted an analysis of alle...

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Detalles Bibliográficos
Autores principales: He, Liang, Loika, Yury, Kulminski, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016079/
https://www.ncbi.nlm.nih.gov/pubmed/35436980
http://dx.doi.org/10.1038/s41398-022-01913-1