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EDP-mitotane in children: reassuring evidence of reversible side-effects and neurotoxicity

Adrenocortical carcinoma affects one in 5 million children each year. Since prognosis for children older than 4 years is limited, clinicians often choose aggressive treatment with etoposide, doxorubicin, cisplatin (EDP) and mitotane after resection. However, little is known about the impact of EDP-m...

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Detalles Bibliográficos
Autores principales: Steenaard, Rebecca V., Rutjens, Marieke, Ettaieb, Madeleine H. T., van Noesel, Max M., Haak, Harm R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016089/
https://www.ncbi.nlm.nih.gov/pubmed/35435506
http://dx.doi.org/10.1007/s12672-022-00486-1