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Single Dose Comparative Bioavailability Study of Lisdexamfetamine Dimesylate as Oral Solution Versus Reference Hard Capsules in Healthy Volunteers

Lisdexamfetamine is an inactive prodrug of dexamfetamine that is used for the second-line treatment of attention-deficit/hyperactivity disorder (ADHD) and moderate to severe binge eating disorder (BED). Once in the blood, the prodrug is hydrolyzed in erythrocyte cytosol, thus releasing the active de...

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Detalles Bibliográficos
Autores principales: Rizea-Savu, Simona, Duna, Simona Nicoleta, Panagiotopoulos, Dimitrios, Sandulovici, Roxana Colette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016112/
https://www.ncbi.nlm.nih.gov/pubmed/35450052
http://dx.doi.org/10.3389/fphar.2022.881198