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Quantitative Comparison of Avian and Mammalian Physiologies for Parameterization of Physiologically Based Kinetic Models

Physiologically based kinetic (PBK) models facilitate chemical risk assessment by predicting in vivo exposure while reducing the need for animal testing. PBK models for mammals have seen significant progress, which has yet to be achieved for avian systems. Here, we quantitatively compare physiologic...

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Detalles Bibliográficos
Autores principales: Scanes, Colin G., Witt, Johannes, Ebeling, Markus, Schaller, Stephan, Baier, Vanessa, Bone, Audrey J., Preuss, Thomas G., Heckmann, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016154/
https://www.ncbi.nlm.nih.gov/pubmed/35450159
http://dx.doi.org/10.3389/fphys.2022.858386