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Quantitative Comparison of Avian and Mammalian Physiologies for Parameterization of Physiologically Based Kinetic Models
Physiologically based kinetic (PBK) models facilitate chemical risk assessment by predicting in vivo exposure while reducing the need for animal testing. PBK models for mammals have seen significant progress, which has yet to be achieved for avian systems. Here, we quantitatively compare physiologic...
Autores principales: | Scanes, Colin G., Witt, Johannes, Ebeling, Markus, Schaller, Stephan, Baier, Vanessa, Bone, Audrey J., Preuss, Thomas G., Heckmann, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016154/ https://www.ncbi.nlm.nih.gov/pubmed/35450159 http://dx.doi.org/10.3389/fphys.2022.858386 |
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