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CRISPR Gene Editing of Human Primary NK and T Cells for Cancer Immunotherapy

Antitumor activity of immune cells such as T cells and NK cells has made them auspicious therapeutic regimens for adaptive cancer immunotherapy. Enhancing their cytotoxic effects against malignancies and overcoming their suppression in tumor microenvironment (TME) may improve their efficacy to treat...

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Detalles Bibliográficos
Autores principales: Elmas, Ezgi, Saljoughian, Noushin, de Souza Fernandes Pereira, Marcelo, Tullius, Brian P., Sorathia, Kinnari, Nakkula, Robin J., Lee, Dean A., Naeimi Kararoudi, Meisam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016158/
https://www.ncbi.nlm.nih.gov/pubmed/35449580
http://dx.doi.org/10.3389/fonc.2022.834002