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High-Dimensional DNA Methylation Mediates the Effect of Smoking on Crohn’s Disease

Epigenome-wide mediation analysis aims to identify high-dimensional DNA methylation at cytosine–phosphate–guanine (CpG) sites that mediate the causal effect of linking smoking with Crohn’s disease (CD) outcome. Studies have shown that smoking has significant detrimental effects on the course of CD....

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Xia, Pingtian, Su, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016182/
https://www.ncbi.nlm.nih.gov/pubmed/35450213
http://dx.doi.org/10.3389/fgene.2022.831885