Composite endpoint for ALS clinical trials based on patient preference: Patient-Ranked Order of Function (PROOF)

BACKGROUND: Patients with amyotrophic lateral sclerosis (ALS) show considerable variation in symptoms. Treatments targeting an overall improvement in symptomatology may not address what the majority of patients consider to be most important. Here, we propose a composite endpoint for ALS clinical tri...

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Detalles Bibliográficos
Autores principales: van Eijk, Ruben P A, van den Berg, L H, Lu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Neuromuscular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016230/
https://www.ncbi.nlm.nih.gov/pubmed/34921121
http://dx.doi.org/10.1136/jnnp-2021-328194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016230/
https://www.ncbi.nlm.nih.gov/pubmed/34921121
http://dx.doi.org/10.1136/jnnp-2021-328194

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