Inhibition of WEE1 Potentiates Sensitivity to PARP Inhibitor in Biliary Tract Cancer

PURPOSE: Up to 20% of patients with biliary tract cancer (BTC) have alterations in DNA damage response (DDR) genes, including homologous recombination (HR) genes. Therefore, the DDR pathway could be a promising target for new drug development in BTC. We aim to investigate the anti-tumor effects usin...

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Detalles Bibliográficos
Autores principales: Seo, Hye-Rim, Nam, Ah-Rong, Bang, Ju-Hee, Oh, Kyoung-Seok, Kim, Jae-Min, Yoon, Jeesun, Kim, Tae-Yong, Oh, Do-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016294/
https://www.ncbi.nlm.nih.gov/pubmed/34352995
http://dx.doi.org/10.4143/crt.2021.473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016294/
https://www.ncbi.nlm.nih.gov/pubmed/34352995
http://dx.doi.org/10.4143/crt.2021.473

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