A Hypoxia-Induced SCF(FBXL1) E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis

PURPOSE: Emerging evidence has shown that SKP1-cullin-1-F-box-protein (SCF) E3 ligases contribute to the pathogenesis of different cancers by mediating the ubiquitination and degradation of tumor suppressors. However, the functions of SCF E3 ligases in the pathogenesis of colorectal cancer (CRC) rem...

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Detalles Bibliográficos
Autores principales: Zeng, Jun, Xiao, Xiao-qing, Zhou, Zhi-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016320/
https://www.ncbi.nlm.nih.gov/pubmed/34237211
http://dx.doi.org/10.4143/crt.2021.373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016320/
https://www.ncbi.nlm.nih.gov/pubmed/34237211
http://dx.doi.org/10.4143/crt.2021.373

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