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Airway secretory cell fate conversion via YAP‐mTORC1‐dependent essential amino acid metabolism

Tissue homeostasis requires lineage fidelity of stem cells. Dysregulation of cell fate specification and differentiation leads to various diseases, yet the cellular and molecular mechanisms governing these processes remain elusive. We demonstrate that YAP/TAZ activation reprograms airway secretory c...

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Detalles Bibliográficos
Autores principales: Jeon, Hae Yon, Choi, Jinwook, Kraaier, Lianne, Kim, Young Hoon, Eisenbarth, David, Yi, Kijong, Kang, Ju‐Gyeong, Kim, Jin Woo, Shim, Hyo Sup, Lee, Joo‐Hyeon, Lim, Dae‐Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016350/
https://www.ncbi.nlm.nih.gov/pubmed/35285539
http://dx.doi.org/10.15252/embj.2021109365