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Airway secretory cell fate conversion via YAP‐mTORC1‐dependent essential amino acid metabolism
Tissue homeostasis requires lineage fidelity of stem cells. Dysregulation of cell fate specification and differentiation leads to various diseases, yet the cellular and molecular mechanisms governing these processes remain elusive. We demonstrate that YAP/TAZ activation reprograms airway secretory c...
Autores principales: | Jeon, Hae Yon, Choi, Jinwook, Kraaier, Lianne, Kim, Young Hoon, Eisenbarth, David, Yi, Kijong, Kang, Ju‐Gyeong, Kim, Jin Woo, Shim, Hyo Sup, Lee, Joo‐Hyeon, Lim, Dae‐Sik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016350/ https://www.ncbi.nlm.nih.gov/pubmed/35285539 http://dx.doi.org/10.15252/embj.2021109365 |
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