Ribociclib Inhibits P-gp-Mediated Multidrug Resistance in Human Epidermoid Carcinoma Cells

The efficacy of cancer chemotherapy can be attenuated or abrogated by multidrug resistance (MDR) in cancer cells. In this study, we determined the effect of the CDK4/6 inhibitor, ribociclib (or LEE011), on P-glycoprotein (P-gp)-mediated MDR in the human epidermoid carcinoma MDR cell line, KB-C2, whi...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Ye, Biwei, Lin, Yunfeng, Li, Yi-Dong, Wang, Jing-Quan, Chen, Zhuo, Ping, Feng-Feng, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016416/
https://www.ncbi.nlm.nih.gov/pubmed/35450042
http://dx.doi.org/10.3389/fphar.2022.867128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016416/
https://www.ncbi.nlm.nih.gov/pubmed/35450042
http://dx.doi.org/10.3389/fphar.2022.867128

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