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Multiple Profile Models Extract Features from Protein Sequence Data and Resolve Functional Diversity of Very Different Protein Families

Functional classification of proteins from sequences alone has become a critical bottleneck in understanding the myriad of protein sequences that accumulate in our databases. The great diversity of homologous sequences hides, in many cases, a variety of functional activities that cannot be anticipat...

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Detalles Bibliográficos
Autores principales: Vicedomini, R., Bouly, J.P., Laine, E., Falciatore, A., Carbone, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016551/
https://www.ncbi.nlm.nih.gov/pubmed/35353898
http://dx.doi.org/10.1093/molbev/msac070