Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation

Vertebrate lonesome kinase (VLK) is the only known extracellular tyrosine kinase, but its physiological functions are largely unknown. We show that VLK is highly expressed in hepatocytes of neonatal mice, but downregulated during adulthood. To determine the role of VLK in liver homeostasis and regen...

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Detalles Bibliográficos
Autores principales: Pantasis, Sophia, Friemel, Juliane, Brütsch, Salome Mirjam, Hu, Zehan, Krautbauer, Sabrina, Liebisch, Gerhard, Dengjel, Joern, Weber, Achim, Werner, Sabine, Bordoli, Mattia Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016620/
https://www.ncbi.nlm.nih.gov/pubmed/35293576
http://dx.doi.org/10.1242/jcs.259243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016620/
https://www.ncbi.nlm.nih.gov/pubmed/35293576
http://dx.doi.org/10.1242/jcs.259243

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