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Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells

Cancer cells exploit a variety of migration modes to leave primary tumors and establish metastases, including amoeboid cell migration, which is typically reliant on bleb formation. Here we demonstrate that thrombin induces dynamic blebbing in the MDA-MB-231 breast cancer cell line and confirm that p...

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Detalles Bibliográficos
Autores principales: O'Callaghan, Paul, Engberg, Adam, Eriksson, Olle, Fatsis-Kavalopoulos, Nikos, Stelzl, Christina, Sanchez, Gonzalo, Idevall-Hagren, Olof, Kreuger, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016622/
https://www.ncbi.nlm.nih.gov/pubmed/35274124
http://dx.doi.org/10.1242/jcs.258809