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Evolution of nasal and olfactory infection characteristics of SARS-CoV-2 variants

SARS-CoV-2 infection of the upper airway and the subsequent immune response are early, critical factors in COVID-19 pathogenesis. By studying infection of human biopsies in vitro and in a hamster model in vivo, we demonstrated a transition in tropism from olfactory to respiratory epithelium as the v...

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Detalles Bibliográficos
Autores principales: Chen, Mengfei, Pekosz, Andrew, Villano, Jason S., Shen, Wenjuan, Zhou, Ruifeng, Kulaga, Heather, Li, Zhexuan, Beck, Sarah E., Witwer, Kenneth W., Mankowski, Joseph L., Ramanathan, Murugappan, Rowan, Nicholas R., Lane, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016639/
https://www.ncbi.nlm.nih.gov/pubmed/35441175
http://dx.doi.org/10.1101/2022.04.12.487379