Enzymatic Hydrolysis of Human Milk Oligosaccharides. The Molecular Mechanism of Bifidobacterium Bifidum Lacto-N-biosidase

[Image: see text] Bifidobacterium bifidum lacto-N-biosidase (LnbB) is a critical enzyme for the degradation of human milk oligosaccharides in the gut microbiota of breast-fed infants. Guided by recent crystal structures, we unveil its molecular mechanism of catalysis using QM/MM metadynamics. We sho...

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Detalles Bibliográficos
Autores principales: Cuxart, Irene, Coines, Joan, Esquivias, Oriol, Faijes, Magda, Planas, Antoni, Biarnés, Xevi, Rovira, Carme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016705/
https://www.ncbi.nlm.nih.gov/pubmed/35465242
http://dx.doi.org/10.1021/acscatal.2c00309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016705/
https://www.ncbi.nlm.nih.gov/pubmed/35465242
http://dx.doi.org/10.1021/acscatal.2c00309

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