Genome-wide CRISPR Screening to Identify Drivers of TGF-β-Induced Liver Fibrosis in Human Hepatic Stellate Cells

[Image: see text] Liver fibrosis progression in chronic liver disease leads to cirrhosis, liver failure, or hepatocellular carcinoma and often ends in liver transplantation. Even with an increased understanding of liver fibrogenesis and many attempts to generate therapeutics specifically targeting f...

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Detalles Bibliográficos
Autores principales: Yu, Shan, Ericson, Matthew, Fanjul, Andrea, Erion, Derek M., Paraskevopoulou, Maria, Smith, Erin N., Cole, Banumathi, Feaver, Ryan, Holub, Corine, Gavva, Narender, Horman, Shane R., Huang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016707/
https://www.ncbi.nlm.nih.gov/pubmed/35274923
http://dx.doi.org/10.1021/acschembio.2c00006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016707/
https://www.ncbi.nlm.nih.gov/pubmed/35274923
http://dx.doi.org/10.1021/acschembio.2c00006

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