Substrate Recognition by the Peptidyl-(S)-2-mercaptoglycine Synthase TglHI during 3-Thiaglutamate Biosynthesis

[Image: see text] 3-Thiaglutamate is a recently identified amino acid analog originating from cysteine. During its biosynthesis, cysteinyl-tRNA is first enzymatically appended to the C-terminus of TglA, a 50-residue ribosomally translated peptide scaffold. After hydrolytic removal of the tRNA, this...

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Detalles Bibliográficos
Autores principales: McLaughlin, Martin I., Yu, Yue, van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016710/
https://www.ncbi.nlm.nih.gov/pubmed/35362960
http://dx.doi.org/10.1021/acschembio.2c00087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016710/
https://www.ncbi.nlm.nih.gov/pubmed/35362960
http://dx.doi.org/10.1021/acschembio.2c00087

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