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Interconversion between Serum Amyloid A Native and Fibril Conformations
[Image: see text] Overexpression of serum amyloid A (SAA) can lead to a form of amyloidosis where the fibrils are made of SAA fragments, most often SAA(1–76). Using Replica Exchange with Tunneling, we study the conversion of a SAA(1–76) chain between the folded conformation and a fibril conformation...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016813/ https://www.ncbi.nlm.nih.gov/pubmed/35449919 http://dx.doi.org/10.1021/acsomega.2c00566 |