Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers

Methylation of cytosines on DNA is a prominent modification associated with gene expression regulation. Aberrant DNA methylation patterns have recurrently been linked to dysregulation of the regulatory program in cancer cells. To shed light on the underlying molecular mechanism driving this process,...

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Detalles Bibliográficos
Autores principales: Lemma, Roza Berhanu, Fleischer, Thomas, Martinsen, Emily, Ledsaak, Marit, Kristensen, Vessela, Eskeland, Ragnhild, Gabrielsen, Odd Stokke, Mathelier, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016969/
https://www.ncbi.nlm.nih.gov/pubmed/35440061
http://dx.doi.org/10.1186/s13072-022-00444-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016969/
https://www.ncbi.nlm.nih.gov/pubmed/35440061
http://dx.doi.org/10.1186/s13072-022-00444-9

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