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Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis

BACKGROUND: Endometrial cancer is the most common gynaecological cancer in high-income countries. Elevated body mass index (BMI) is an established modifiable risk factor for this condition and is estimated to confer a larger effect on endometrial cancer risk than any other cancer site. However, the...

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Detalles Bibliográficos
Autores principales: Hazelwood, Emma, Sanderson, Eleanor, Tan, Vanessa Y., Ruth, Katherine S., Frayling, Timothy M., Dimou, Niki, Gunter, Marc J., Dossus, Laure, Newton, Claire, Ryan, Neil, Pournaras, Dimitri J., O’Mara, Tracy A., Davey Smith, George, Martin, Richard M., Yarmolinsky, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017004/
https://www.ncbi.nlm.nih.gov/pubmed/35436960
http://dx.doi.org/10.1186/s12916-022-02322-3