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Integrative analysis of mutated genes and mutational processes reveals novel mutational biomarkers in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Recent studies have observed causative mutations in susceptible genes related to colorectal cancer in 10 to 15% of the patients. This highlights the importance of identifying mutations for early dete...

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Detalles Bibliográficos
Autores principales: Dashti, Hamed, Dehzangi, Iman, Bayati, Masroor, Breen, James, Beheshti, Amin, Lovell, Nigel, Rabiee, Hamid R., Alinejad-Rokny, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017053/
https://www.ncbi.nlm.nih.gov/pubmed/35439935
http://dx.doi.org/10.1186/s12859-022-04652-8