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Integrative analysis of mutated genes and mutational processes reveals novel mutational biomarkers in colorectal cancer
BACKGROUND: Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Recent studies have observed causative mutations in susceptible genes related to colorectal cancer in 10 to 15% of the patients. This highlights the importance of identifying mutations for early dete...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017053/ https://www.ncbi.nlm.nih.gov/pubmed/35439935 http://dx.doi.org/10.1186/s12859-022-04652-8 |