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Expression, purification, and biophysical characterization of recombinant MERS-CoV main (M(pro)) protease
MERS-CoV main protease (M(pro)) is essential for the maturation of the coronavirus; therefore, considered a potential drug target. Detailed conformational information is essential to developing antiviral therapeutics. However, the conformation of MERS-CoV M(pro) under different conditions is poorly...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017057/ https://www.ncbi.nlm.nih.gov/pubmed/35452699 http://dx.doi.org/10.1016/j.ijbiomac.2022.04.077 |