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Expression, purification, and biophysical characterization of recombinant MERS-CoV main (M(pro)) protease

MERS-CoV main protease (M(pro)) is essential for the maturation of the coronavirus; therefore, considered a potential drug target. Detailed conformational information is essential to developing antiviral therapeutics. However, the conformation of MERS-CoV M(pro) under different conditions is poorly...

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Detalles Bibliográficos
Autores principales: Almutairi, Ghada Obeid, Malik, Ajamaluddin, Alonazi, Mona, Khan, Javed Masood, Alhomida, Abdullah S., Khan, Mohd Shahnawaz, Alenad, Amal M., Altwaijry, Nojood, Alafaleq, Nouf Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017057/
https://www.ncbi.nlm.nih.gov/pubmed/35452699
http://dx.doi.org/10.1016/j.ijbiomac.2022.04.077