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Expression, purification, and biophysical characterization of recombinant MERS-CoV main (M(pro)) protease

MERS-CoV main protease (M(pro)) is essential for the maturation of the coronavirus; therefore, considered a potential drug target. Detailed conformational information is essential to developing antiviral therapeutics. However, the conformation of MERS-CoV M(pro) under different conditions is poorly...

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Detalles Bibliográficos
Autores principales:	Almutairi, Ghada Obeid, Malik, Ajamaluddin, Alonazi, Mona, Khan, Javed Masood, Alhomida, Abdullah S., Khan, Mohd Shahnawaz, Alenad, Amal M., Altwaijry, Nojood, Alafaleq, Nouf Omar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017057/ https://www.ncbi.nlm.nih.gov/pubmed/35452699 http://dx.doi.org/10.1016/j.ijbiomac.2022.04.077

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