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Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment
Master transcription factors (TFs) directly regulate present and future cell states by binding DNA regulatory elements and driving gene-expression programs. Their abundance influences epigenetic priming to different cell fates at the chromatin level, especially in the context of differentiation. In...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017139/ https://www.ncbi.nlm.nih.gov/pubmed/35463156 http://dx.doi.org/10.1016/j.crmeth.2022.100188 |