Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment

Master transcription factors (TFs) directly regulate present and future cell states by binding DNA regulatory elements and driving gene-expression programs. Their abundance influences epigenetic priming to different cell fates at the chromatin level, especially in the context of differentiation. In...

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Detalles Bibliográficos
Autores principales: Baskar, Reema, Chen, Amy F., Favaro, Patricia, Reynolds, Warren, Mueller, Fabian, Borges, Luciene, Jiang, Sizun, Park, Hyun Shin, Kool, Eric T., Greenleaf, William J., Bendall, Sean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017139/
https://www.ncbi.nlm.nih.gov/pubmed/35463156
http://dx.doi.org/10.1016/j.crmeth.2022.100188

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