Cargando…

A widely distributed HIV-1 provirus elimination assay to evaluate latency-reversing agents in vitro

Persistence of HIV-1 latent reservoir cells during antiretroviral therapy (ART) is a major obstacle for curing HIV-1. Even though latency-reversing agents (LRAs) are under development to reactivate and eradicate latently infected cells, there are few useful models for evaluating LRA activity in vitr...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsuda, Kouki, Islam, Saiful, Takada, Toru, Tsuchiya, Kiyoto, Yang Tan, Benjy Jek, Hattori, Shin-ichiro, Katsuya, Hiroo, Kitagawa, Kosaku, Kim, Kwang Su, Matsuo, Misaki, Sugata, Kenji, Delino, Nicole S., Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Matsushita, Shuzo, Mitsuya, Hiroaki, Iwami, Shingo, Satou, Yorifumi, Maeda, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017183/
https://www.ncbi.nlm.nih.gov/pubmed/35475215
http://dx.doi.org/10.1016/j.crmeth.2021.100122