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High-throughput 5′P sequencing enables the study of degradation-associated ribosome stalls

RNA degradation is critical for gene expression and mRNA quality control. mRNA degradation is connected to the translation process up to the degree that 5′-3′ mRNA degradation follows the last translating ribosome. Here, we present an improved high-throughput 5′P degradome RNA-sequencing method (HT-...

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Detalles Bibliográficos
Autores principales: Zhang, Yujie, Pelechano, Vicent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017187/
https://www.ncbi.nlm.nih.gov/pubmed/35474692
http://dx.doi.org/10.1016/j.crmeth.2021.100001