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Probe design for simultaneous, targeted capture of diverse metagenomic targets
The compounding challenges of low signal, high background, and uncertain targets plague many metagenomic sequencing efforts. One solution has been DNA capture, wherein probes are designed to hybridize with target sequences, enriching them in relation to their background. However, balancing probe dep...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017208/ https://www.ncbi.nlm.nih.gov/pubmed/35474894 http://dx.doi.org/10.1016/j.crmeth.2021.100069 |