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Probe design for simultaneous, targeted capture of diverse metagenomic targets

The compounding challenges of low signal, high background, and uncertain targets plague many metagenomic sequencing efforts. One solution has been DNA capture, wherein probes are designed to hybridize with target sequences, enriching them in relation to their background. However, balancing probe dep...

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Detalles Bibliográficos
Autores principales: Dickson, Zachery W., Hackenberger, Dirk, Kuch, Melanie, Marzok, Art, Banerjee, Arinjay, Rossi, Laura, Klowak, Jennifer Ann, Fox-Robichaud, Alison, Mossmann, Karen, Miller, Matthew S., Surette, Michael G., Golding, Geoffrey Brian, Poinar, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017208/
https://www.ncbi.nlm.nih.gov/pubmed/35474894
http://dx.doi.org/10.1016/j.crmeth.2021.100069