Discovery and validation of human genomic safe harbor sites for gene and cell therapies

Existing approaches to therapeutic gene transfer are marred by the transient nature of gene expression following non-integrative gene delivery and by safety concerns due to the random mechanism of viral-mediated genomic insertions. The disadvantages of these methods encourage future research in iden...

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Detalles Bibliográficos
Autores principales: Aznauryan, Erik, Yermanos, Alexander, Kinzina, Elvira, Devaux, Anna, Kapetanovic, Edo, Milanova, Denitsa, Church, George M., Reddy, Sai T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017210/
https://www.ncbi.nlm.nih.gov/pubmed/35474867
http://dx.doi.org/10.1016/j.crmeth.2021.100154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017210/
https://www.ncbi.nlm.nih.gov/pubmed/35474867
http://dx.doi.org/10.1016/j.crmeth.2021.100154

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