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A pan-cancer survey of cell line tumor similarity by feature-weighted molecular profiles
Patient-derived cell lines are often used in pre-clinical cancer research, but some cell lines are too different from tumors to be good models. Comparison of genomic and expression profiles can guide the choice of pre-clinical models, but typically not all features are equally relevant. We present T...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017219/ https://www.ncbi.nlm.nih.gov/pubmed/35475239 http://dx.doi.org/10.1016/j.crmeth.2021.100039 |