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Heritability Enrichment Implicates Microglia in Parkinson’s Disease Pathogenesis

OBJECTIVE: Understanding how different parts of the immune system contribute to pathogenesis in Parkinson’s disease is a burning challenge with important therapeutic implications. We studied enrichment of common variant heritability for Parkinson’s disease stratified by immune and brain cell types....

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Detalles Bibliográficos
Autores principales: Andersen, Maren Stolp, Bandres-Ciga, Sara, Reynolds, Regina H., Hardy, John, Ryten, Mina, Krohn, Lynne, Gan-Or, Ziv, Holtman, Inge R., Pihlstrøm, Lasse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017316/
https://www.ncbi.nlm.nih.gov/pubmed/33502028
http://dx.doi.org/10.1002/ana.26032