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Identification of Recombinant Chimpanzee Adenovirus C68 Degradation Products Detected by AEX-HPLC

Physicochemical tests represent important tools for the analytical control strategy of biotherapeutics. For adenoviral modalities, anion-exchange high performance liquid chromatography (AEX-HPLC) represents an important methodology, as it is able to simultaneously provide information on viral partic...

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Detalles Bibliográficos
Autores principales: Powers, Thomas W., Mullins, Elise K., Zhang, Kun, Binder, Joseph J., Friese, Olga, Runnels, Herbert A., Thompson, Lawrence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017566/
https://www.ncbi.nlm.nih.gov/pubmed/35449595
http://dx.doi.org/10.3389/fbioe.2022.753481