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Identification of Recombinant Chimpanzee Adenovirus C68 Degradation Products Detected by AEX-HPLC
Physicochemical tests represent important tools for the analytical control strategy of biotherapeutics. For adenoviral modalities, anion-exchange high performance liquid chromatography (AEX-HPLC) represents an important methodology, as it is able to simultaneously provide information on viral partic...
Autores principales: | Powers, Thomas W., Mullins, Elise K., Zhang, Kun, Binder, Joseph J., Friese, Olga, Runnels, Herbert A., Thompson, Lawrence C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017566/ https://www.ncbi.nlm.nih.gov/pubmed/35449595 http://dx.doi.org/10.3389/fbioe.2022.753481 |
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