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m(6)A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels

BACKGROUND: Methyltransferase 3 (METTL3)‐mediated N6‐methyladenosine (m(6)A) RNA modification has been demonstrated to be a potential factor in promoting gastric cancer (GC). METTL3 regulates a series of signaling pathways by modifying various mRNAs. This study aimed to identify novel METTL3‐mediate...

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Detalles Bibliográficos
Autores principales: Liu, Yinan, Zhai, Ertao, Chen, Junting, Qian, Yan, Zhao, Risheng, Ma, Yan, Liu, Jianqiu, Huang, Zhixin, Cai, Shirong, Chen, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017753/
https://www.ncbi.nlm.nih.gov/pubmed/35261206
http://dx.doi.org/10.1002/cac2.12281