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Mesenchymal Stem Cell–Derived Extracellular Vesicles Alleviate M1 Microglial Activation in Brain Injury of Mice With Subarachnoid Hemorrhage via microRNA-140-5p Delivery

BACKGROUND: It is documented that mesenchymal stem cells (MSCs) secrete extracellular vesicles (EVs) to modulate subarachnoid hemorrhage (SAH) development. miR-140-5p expression has been detected in MSC-derived EVs, while the mechanism of MSC-derived EVs containing miR-140-5p in SAH remains unknown....

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Detalles Bibliográficos
Autores principales: Qian, Yu, Li, Qiaoyu, Chen, Lulu, Sun, Jinyu, Cao, Kan, Mei, Zhaojun, Lu, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017768/
https://www.ncbi.nlm.nih.gov/pubmed/35015859
http://dx.doi.org/10.1093/ijnp/pyab096