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Mitochondria Transfer to CD4(+) T Cells May Alleviate Rheumatoid Arthritis by Suppressing Pro-Inflammatory Cytokine Production

CD4(+) T cells contribute to the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA). These cells infiltrate the joints of RA patients and produce cytokines, including Tumor necrosis factor (TNF)-α, that drive joint inflammation and bone destruction. Although biologic therapeutics...

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Detalles Bibliográficos
Autores principales: Giwa, Rocky, Brestoff, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017867/
https://www.ncbi.nlm.nih.gov/pubmed/35444834
http://dx.doi.org/10.20900/immunometab20220009