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The expression of virulence genes increases membrane permeability and sensitivity to envelope stress in Salmonella Typhimurium

Virulence gene expression can represent a substantial fitness cost to pathogenic bacteria. In the model entero-pathogen Salmonella Typhimurium (S.Tm), such cost favors emergence of attenuated variants during infections that harbor mutations in transcriptional activators of virulence genes (e.g., hil...

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Detalles Bibliográficos
Autores principales: Sobota, Malgorzata, Rodilla Ramirez, Pilar Natalia, Cambré, Alexander, Rocker, Andrea, Mortier, Julien, Gervais, Théo, Haas, Tiphaine, Cornillet, Delphine, Chauvin, Dany, Hug, Isabelle, Julou, Thomas, Aertsen, Abram, Diard, Médéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017878/
https://www.ncbi.nlm.nih.gov/pubmed/35389980
http://dx.doi.org/10.1371/journal.pbio.3001608