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Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi

Lymphatic filariasis (LF) is a chronic debilitating neglected tropical disease (NTD) caused by mosquito-transmitted nematodes that afflicts over 60 million people. Control of LF relies on routine mass drug administration with antiparasitics that clear circulating larval parasites but are ineffective...

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Detalles Bibliográficos
Autores principales: Airs, Paul M., Vaccaro, Kathy, Gallo, Kendra J., Dinguirard, Nathalie, Heimark, Zachary W., Wheeler, Nicolas J., He, Jiaye, Weiss, Kurt R., Schroeder, Nathan E., Huisken, Jan, Zamanian, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017939/
https://www.ncbi.nlm.nih.gov/pubmed/35390105
http://dx.doi.org/10.1371/journal.ppat.1010399