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Phylogenetic profiling resolves early emergence of PRC2 and illuminates its functional core

Polycomb repressive complex 2 (PRC2) is involved in maintaining transcriptionally silent chromatin states through methylating lysine 27 of histone H3 by the catalytic subunit enhancer of zeste [E(z)]. Here, we report the diversity of PRC2 core subunit proteins in different eukaryotic supergroups wit...

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Detalles Bibliográficos
Autores principales: Sharaf, Abdoallah, Vijayanathan, Mallika, Oborník, Miroslav, Mozgová, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018016/
https://www.ncbi.nlm.nih.gov/pubmed/35440471
http://dx.doi.org/10.26508/lsa.202101271